Deerfield Management Companies

Molecular Assay & Testing Analyst

Job Locations US-MD-Gaithersburg
Job Post Information* : Posted Date 4 weeks ago(11/5/2021 11:34 AM)
ID
2021-1623
# of Openings
1
Category
Scientist

Overview

Exciting opportunity for experienced individual to join the team at Adaptive Phage Therapeutics (APT). APT is a clinical-stage biotech company advancing therapies to treat multi-drug resistant infections. APT is seeking a highly motivated individual skilled in a broad range of wet bench microbiology and molecular biology techniques with expertise in viral/bacteriophage biology, genomics and NGS sequencing operations. The successful candidate will be responsible for independently performing assays in a fast paced and energetic environment under supervision of the Associate Director of Molecular Assays & Testing within the Quality Group.

Responsibilities

Reasonable accommodations may be made to enable individuals with disabilities to perform these essential functions.

  • Development, optimization and implementation of an appropriate and controlled DNA extraction and sequencing pipeline.
  • NGS library prep and operation of Illumina sequencers. Experience with Oxford Nanopore a plus.
  • Conduct a range of molecular QC tests which may include 16S PCR, restriction digests, qPCR, nucleic acid quantitation and quality assessments.
  • Experience with tech transfer of manual protocols to various scalable and automated formats/platforms.
  • Primary QC analysis of sequencing data using basic bioinformatic tools.
  • Develop/execute/document procedures for production and quality control of genome data in a regulated environment.
  • Support QA management in the establishment, writing, editing and implementation of formal SOPs, forms, deviations and other required documents in accordance with cGMP.
  • Coordinate and present data to internal stakeholders and external business partners.
  • Troubleshoot issues relating to both existing and new laboratory techniques and provide feedback and potential solutions to senior leadership.
  • Excellent pipetting and multi-channel pipetting skills required
  • Programming/scripting/database experience a plus (LIMS, Python, unix, SQL, others)
  • Other duties as needed

Competencies:

  • Outstanding communication, collaboration, and problem solving
  • Excellent work ethic, ability to work independently as well as in a team
  • Ability to multitask while still achieving primary goals
  • Shows initiative in suggesting and executing process improvements
  • Careful, well-organized and detail-oriented working style

Please note this job description is not an all-encompassing and comprehensive list of activities, duties or responsibilities that are required of the employee for this job. Duties, responsibilities, and activities may change at any time with or without notice.

Qualifications

  • Bachelor or Masters Degree in Biology, Life Sciences, or a related discipline.
  • 3-5 years’ laboratory experience
  • Basic knowledge of general laboratory techniques and proficiency with commonly used equipment
  • Basic subject matter knowledge in microbiology, biology, chemistry, biotechnology, genetics and genomics
  • Combination of QA and QC or manufacturing experience a plus

Full COVID-19 vaccination required; Since APT is a government contractor, all employees are required to be fully vaccinated against COVID-19 to work onsite.

Candidates will be provided a copy of the physical, environmental & mental demands upon request. 

 

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